Glycerin and propylene glycol are of low toxicity when consumed. Nicotine is the bigger issue. Whether any of the compounds are toxic when inhaled long term is not currently known.
The nicotine levels in these e-liquids can vary in concentration from being completely nicotine-free up to 36 milligrams per milliliter of nicotine.
An e-cig with a full cartridge can contain up to 36 mg of nicotine, which doesn’t sound like a lot until you factor in how toxic nicotine is. Clinical signs of nicotine poisoning can be seen in dogs and cats exposed to a mere 0.5 mg per pound of body weight. For cats and small dogs, ingesting 20 mg of nicotine can be lethal.
Even more dangerous are the refill bottles of e-liquid that are used to recharge the e-cig cartridge. The nicotine in these bottles can range from 10 mL to 60 mL or more. So a 30-mL bottle can be more than enough to prove fatal for even a very large dog if ingested.
Nicotine is readily absorbed by ingestion as well as through the skin. Pets may be exposed when they chew up the e-cigs or the bottles containing e-juice, or even when they walk through puddles of spilled e-juice and get it on their paws. The signs of nicotine poisoning may begin within 15 to 30 minutes of exposure; in contrast, signs of nicotine poisoning following eating tobacco products may take a few hours as the nicotine must be released from the tobacco.
The first signs normally seen with toxic exposure to nicotine include:
- Excessive drooling (hypersalivation)
- Vomiting with or without diarrhea
- Agitation or restlessness
- Increased respiratory rate or panting.
With severe intoxications, signs may progress to include:
- Convulsions or seizures
- Increased heart rate
- Increased blood pressure.
Further progression of signs may result in profound weakness, paralysis, abnormal heart rhythms (including cardiac arrest), hypotension, coma and death.
Prompt and aggressive veterinary care is required to successfully manage poisoning from electronic cigarette liquid exposure. Because the e-juice is rapidly absorbed across the mucous membranes of the mouth, standard decontamination measures such as inducing vomiting are usually not helpful. Treatment includes managing convulsions and seizures, treating heart and blood pressure abnormalities, ensuring adequate respiration, and providing intravenous fluids to enhance nicotine elimination.
The prognosis for patients exposed to large amounts of nicotine can be quite grave depending on how quickly veterinary care is obtained, and even with aggressive veterinary care some patients will not survive.
So be careful where you place your electric cigarette devices and store your refill containers
If you feel your pet has ingested nicotine from an electronic cigarette please contact poison control immediately at (888) 426-4435 or Meadowlands Veterinary Hospital at 201-646-2008 or visit us at www.meadowlandsvethospital.com